社区居住老年人Kihon检查表口腔功能评分与全因死亡率之间的关联
Association Between Kihon Checklist Oral-Function Score and All-Cause Mortality in Community-Dwelling Older Adults.
文献信息
| PMID | 42754543 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Kensuke Uraguchi |
| 作者单位 | Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan. |
| 期刊 | Journal of the American Geriatrics Society |
| SCI 分区 | Q1 |
| IF | 5.2 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 咽喉科 |
中文摘要
背景： 我们研究了基于三种自我报告症状（咀嚼困难、吞咽困难和口干症）的Kihon检查表（KCL）口腔功能评分（0-3分）是否与社区居住老年人的全因死亡率相关。
方法： 这项队列研究纳入了52,789名年龄≥65岁的成年人，他们在日本冈山市接受了市政健康检查（2006-2007财政年度），并在2016年12月期间进行了死亡率随访。KCL口腔功能评分（范围0-3分）是三个口腔功能项目阳性回答的总和。使用Cox比例风险模型估计调整后的风险比（aHR）。二次分析使用单独和相互调整的模型检查了每种症状的关联。
结果： 较高的KCL口腔功能评分与全因死亡率增加呈正相关。在完全调整模型中（n=49,665），评分1、2和3的aHR（95%置信区间[CI]）分别为1.09（1.04-1.13）、1.26（1.20-1.32）和1.49（1.38-1.60）。咀嚼困难（aHR 1.19 [95% CI 1.14-1.23]）和吞咽困难（aHR 1.18 [95% CI 1.14-1.23]）各自独立地与死亡率相关，而口干症则不然（aHR 1.02 [95% CI 0.98-1.06]）。
结论： 较高的KCL口腔功能评分与全因死亡率呈正相关。咀嚼困难和吞咽困难与死亡率独立相关，而口干症则不然。基于症状的口腔功能筛查可能有助于识别死亡风险升高的老年人。
英文摘要
BACKGROUND: We examined whether the Kihon Checklist (KCL) oral-function score (0-3), based on three self-reported symptoms (chewing difficulty, dysphagia, and xerostomia), was associated with all-cause mortality in community-dwelling older adults.
METHODS: This cohort study included 52,789 adults aged ≥ 65 years who underwent municipal health checkups in Okayama City, Japan (fiscal year 2006-2007) with mortality follow-ups during December 2016. The KCL oral-function score (range 0-3) was the sum of the positive responses to the three oral-function items. Cox proportional hazards models were used to estimate adjusted hazard ratios (aHR). Secondary analysis examined the association of each symptom using separate and mutually adjusted models.
RESULTS: Higher KCL oral-function scores were positively associated with increased all-cause mortality. In the fully adjusted model (n = 49,665), the aHRs (95% confidence interval [CI]) for scores 1, 2, and 3 were 1.09 (1.04-1.13), 1.26 (1.20-1.32), and 1.49 (1.38-1.60), respectively. Chewing difficulty (aHR 1.19 [95% CI 1.14-1.23]) and dysphagia (aHR 1.18 [95% CI 1.14-1.23]) were each independently associated with mortality, whereas xerostomia was not (aHR 1.02 [95% CI 0.98-1.06]).
CONCLUSIONS: Higher KCL oral-function scores showed a positive association with all-cause mortality. Chewing difficulty and dysphagia were independently associated with mortality, whereas xerostomia was not. Symptom-based oral-function screening may help identify older adults at an elevated mortality risk.