慢性中耳炎伴咽鼓管功能障碍中同期球囊咽鼓管成形术与I型鼓室成形术：一项倾向性评分匹配队列研究
Concurrent balloon eustachian tuboplasty and type I tympanoplasty in chronic otitis media with eustachian tube dysfunction: a propensity score-matched cohort study.
文献信息
| PMID | 42752337 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Lixin Wang |
| 作者单位 | Department of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Wannan Medical University (Yijishan Hospital of Wannan Medical University), Wuhu city, Anhui Province, China. |
| 期刊 | Acta oto-laryngologica |
| SCI 分区 | Q3 |
| IF | 1.3 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 耳科 |
中文摘要
背景： 咽鼓管功能障碍（ETD）可能损害慢性化脓性中耳炎（CSOM）I型鼓室成形术后的移植物结局。
目的： 比较同期球囊咽鼓管成形术（BET）联合鼓室成形术与单纯鼓室成形术在伴ETD的CSOM中的效果。
材料与方法： 这项回顾性倾向性评分匹配队列纳入2021年5月至2024年4月接受治疗的伴ETD的CSOM患者。主要终点为24个月鼓膜完整性；次要终点为气骨导差（ABG）闭合、ETDQ-7、咽鼓管测压及并发症。
结果： 共分析60对匹配病例。24个月时，BET联合鼓室成形术的移植物完整性高于单纯鼓室成形术（57/60，95.0% vs. 49/60，81.7%）；BET与较低的移植物失败风险相关（HR 0.28，95% CI 0.11-0.74；p = 0.024）。联合组还具有更大的ABG闭合（10.3 ± 3.4 vs. 5.4 ± 3.8 dB）、更低的ETDQ-7评分（11.2 ± 2.4 vs. 15.8 ± 3.5）以及更频繁的TMM正常化（86.7% vs. 58.3%）（所有p < 0.001）。未发生严重并发症。
结论： 同期BET与更好的长期移植物、听力及ETD相关结局相关。
英文摘要
BACKGROUND: Eustachian tube dysfunction (ETD) may impair graft outcomes after type I tympanoplasty in chronic suppurative otitis media (CSOM).
OBJECTIVE: To compare concurrent balloon Eustachian tuboplasty (BET) plus tympanoplasty with tympanoplasty alone in CSOM with ETD.
MATERIALS AND METHODS: This retrospective propensity score-matched cohort included CSOM patients with ETD treated from May 2021 to April 2024. The primary endpoint was 24-month tympanic membrane integrity; secondary endpoints were air-bone gap (ABG) closure, ETDQ-7, tubo-manometry, and complications.
RESULTS: Sixty matched pairs were analyzed. At 24 months, graft integrity was higher with BET plus tympanoplasty than with tympanoplasty alone (57/60, 95.0% vs. 49/60, 81.7%); BET was associated with lower graft-failure hazard (HR 0.28, 95% CI 0.11-0.74; p = 0.024). The combined group also had greater ABG closure (10.3 ± 3.4 vs. 5.4 ± 3.8 dB), lower ETDQ-7 scores (11.2 ± 2.4 vs. 15.8 ± 3.5), and more frequent TMM normalization (86.7% vs. 58.3%) (all p < 0.001). No severe complications occurred.
CONCLUSION: Concurrent BET was associated with better long-term graft, hearing, and ETD-related outcomes.