人工耳蜗电极阻抗：一项为期5年的研究

文献信息

中文摘要

背景： 电极阻抗（EI）监测对于理解电极-组织界面动力学以及确保人工耳蜗（CI）植入者获得一致的神经刺激至关重要。
方法： 这项回顾性队列研究在5年期间考察了79例CI植入者（136只植入耳）的长期EI模式。在术中以及植入后1年和5年时，对12个电极进行阻抗测量，并将其分为顶部（电极1-4）、中部（5-8）和底部（9-12）区域。
结果： 顶部区域在5年分析期间显示阻抗稳定，无显著变化。与术中值相比，中部和底部电极在1年和5年评估时均表现出阻抗显著增加。但在1年和5年评估之间未发生显著进展，表明阻抗在1年内初步稳定后，在长期内保持稳定。
结论： 电极阵列周围的生物学反应主要作为术后早期事件发生，随后趋于稳定而非进展。动态阻抗模式强调了术后第一年内定期监测的重要性。它们还提示可能需要个体化的映射策略。

英文摘要

BACKGROUND: Electrode impedance (EI) monitoring is vital for understanding electrode-tissue interface dynamics and ensuring consistent neural stimulation in cochlear implant (CI) recipients.
METHODS: This retrospective cohort study examined long-term EI patterns in 79 CI recipients (136 implanted ears) over a 5-year period. Impedance measurements were obtained intraoperatively and at 1 and 5 years post-implantation across 12 electrodes, categorized into apical (electrodes 1-4), middle (5-8), and basal (9-12) regions.
RESULTS: The apical region showed stable impedance throughout the 5-year analysis, with no significant changes. Middle and basal electrodes exhibited significant increases in impedance at both the 1- and 5-year assessments compared with intraoperative values. But no significant progression occurred between the 1- and 5-year assessments, indicating that impedance stabilized for long-term duration after its initial stabilization within the 1-year period.
CONCLUSION: The biological response surrounding the electrode array occurs predominantly as an early postoperative event that subsequently stabilizes rather than progresses. The dynamic impedance patterns underscore the importance of regular monitoring during the initial postoperative year. They also suggest that individualized mapping strategies may be required.