基于颞骨计算机断层扫描的粘连性中耳炎风险预测列线图：一项回顾性研究
A Prediction Nomogram for the Risk of Adhesive Otitis Media Based on Temporal Bone Computed Tomography: A Retrospective Study.
文献信息
| PMID | 42732619 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Jiawei Chen |
| 作者单位 | Department of Otolaryngology-Head and Neck Surgery, Xijing Hospital, Air Force Medical University, Xi'an, China. |
| 期刊 | The journal of international advanced otology |
| SCI 分区 | Q3 |
| IF | 1.3 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 耳科 |
中文摘要
背景： 基于颞骨计算机断层扫描（CT）开发预测粘连性中耳炎风险的列线图模型。
方法： 进行了一项回顾性横断面研究，分析诊断为粘连性中耳炎（AdOM）患者的颞骨高分辨率CT图像。比较各组之间颞骨解剖变异的发病率。开发并验证了预测AdOM风险的列线图。
结果： 共分析了来自110名患者的153只耳。在AdOM组中，86%的病例存在乳突气化不良（MC0/MC1）。高颈静脉球（HJB）、颈静脉球裂开和乳突窦缺如的发病率分别为45.4%、6.4%和2.7%。与对照组相比，HJB的发病率显著更高（P=.047），乙状窦-外耳道（SS-EAC）距离显著更短（P < .001），硬脑膜板深度显著更深（P=.019）。SS-EAC距离缩短被确定为AdOM发病的独立危险因素（比值比=1.34，P < .001）。开发了预测AdOM风险的列线图，其受试者工作特征曲线下面积为0.751。最佳截断值为-0.753，敏感性为64.3%，特异性为80.0%。
结论： HJB的存在、较短的SS-EAC距离和较深的硬脑膜板深度可能与AdOM的较高发病率相关。开发了一种基于颞骨解剖变异的新型列线图，用于预测AdOM风险，以辅助中耳炎治疗的临床决策。
英文摘要
BACKGROUND: To develop a nomogram model for predicting the risk of adhesive otitis media based on temporal bone computed tomography (CT).
METHODS: A retrospective cross-sectional study was performed to analyze high-resolution CT images of the temporal bone in patients diagnosed with adhesive otitis media (AdOM). The comparison of the incidence of anatomical variants of the temporal bone between groups was performed. A nomogram for predicting the risk of AdOM was developed and validated.
RESULTS: A total of 153 ears from 110 patients were analyzed. In the AdOM group, 86% of the cases had poor mastoid pneumatization (MC0/MC1). The incidence rates of high jugular bulb (HJB), jugular bulb dehiscence, and agenesis of the mastoid antrum were 45.4%, 6.4%, and 2.7%. The incidence of HJB was significantly higher (P=.047), the sigmoid sinus-external auditory canal (SS-EAC) distance was significantly shorter (P < .001), and the depth of the dural plate was significantly deeper (P=.019) than in the control. The SS-EAC distance shortening was identified as an independent risk factor for the incidence of AdOM (odds ratio=1.34, P < .001). A nomogram for predicting the risk of AdOM was developed, with an area under the receiver operating characteristic curve of 0.751. The optimal cutoff value was -0.753 with sensitivity of 64.3% and specificity of 80.0%.
CONCLUSION: The presence of HJB, a shorter SS-EAC distance, and a deeper dural plate depth may be associated with a higher incidence of AdOM. A novel nomogram based on anatomical variations of the temporal bone for predicting the risk of AdOM was developed to assist clinical decision-making in the treatment of otitis media.