使用玻璃离子水门汀进行听骨链重建的长期听力学结局：一项12年队列研究。
Long-Term Audiological Outcomes of Ossiculoplasty Using Glass Ionomer Cement: A 12-Year Cohort Study.
文献信息
| PMID | 42732617 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Arda Er |
| 作者单位 | Department of Otolaryngology and Head and Neck Surgery, Cukurova University Faculty of Medicine, Adana, Türkiye. |
| 期刊 | The journal of international advanced otology |
| SCI 分区 | Q3 |
| IF | 1.3 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 耳科 |
中文摘要
背景： 通过比较术前、术后早期和术后晚期的听力学结果，评估使用玻璃离子水门汀（GIC）进行听骨链重建的长期功能性听力结局。本研究是文献中报道使用GIC进行听骨链重建的极长期（长达12年）听力学结局的有限系列之一。
方法： 这项回顾性队列研究纳入了2012年至2024年间接受使用GIC进行听骨链重建的45例患者。在术前、术后早期（3-12个月）和术后晚期评估听力学结局，包括气导（AC）、骨导（BC）、纯音平均听阈和气骨导差（ABG）。根据随访时间将患者分为1-5年组（n=19）、5-10年组（n=12）和≥10年组（n=14）。对听力学参数的变化进行统计分析。
结果： 共纳入45例患者。与术前值相比，术后早期观察到AC阈值和ABG值显著改善（P < .05）。在1至10年随访组中，术后早期ABG结果在晚期随访时基本得以保持。然而，在随访≥10年的患者中，观察到ABG随时间出现统计学显著恶化。
结论： 使用GIC进行听骨链重建可提供显著的早期听力改善，并且这些改善在中期（1-5年）和长期（5-10年）随访中基本得以维持。仅在极长期随访（≥10年）中观察到有限的损害。玻璃离子水门汀仍然是局限性听骨缺损的高度可行选择，至少可提供10年的功能稳定性。
英文摘要
BACKGROUND: To evaluate the long-term functional hearing outcomes of ossicular chain reconstruction using glass ionomer cement (GIC) by comparing preoperative, early postoperative, and late postoperative audiological results. This study presents one of the limited series in the literature reporting very long-term (up to 12 years) audiological outcomes of ossiculoplasty using GIC.
METHODS: This retrospective cohort study included 45 patients who underwent ossicular chain reconstruction using GIC between 2012 and 2024. Audiological outcomes, including air conduction (AC), bone conduction (BC), pure tone average, and air-bone gap (ABG), were evaluated preoperatively, early postoperatively (3-12 months), and late postoperatively. Patients were grouped according to follow-up duration as 1-5 years (n=19), 5-10 years (n=12), and ≥10 years (n=14). Changes in audiological parameters were analyzed statistically.
RESULTS: A total of 45 patients were included. Significant improvement in AC thresholds and ABG values was observed in the early postoperative period compared to preoperative values (P < .05). In the 1- to 10-year follow-up group, early postoperative ABG results were largely preserved at late follow-up. However, in patients with ≥10 years of follow-up, a statistically significant deterioration in ABG was observed over time.
CONCLUSION: Ossicular reconstruction using GIC provides significant early hearing improvement, and these gains are largely maintained in medium-term (1-5 years) and long-term (5-10 years) follow-up. Limited impairment is observed only in very long-term follow-up (≥10 years). Glass ionomer cement remains a highly viable option for limited ossicular defects, offering functional stability for at least 10 years.