术中eCAP的存在是否能预测成人人工耳蜗植入的结局？
Is the Presence of eCAP Intraoperatively a Predictor of Cochlear Implant Outcomes in Adults?
文献信息
| PMID | 42732139 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Georgea Espindola Ribeiro |
| 作者单位 | Teaching Hospital, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista "Júlio de Mesquita Filho" (UNESP), São Paulo, SP, Brazil. |
| 期刊 | International archives of otorhinolaryngology |
| SCI 分区 | Q3 |
| IF | 1.4 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 耳科 |
中文摘要
引言： 电诱发复合动作电位（eCAP）常用于评估人工耳蜗（CI）使用者听神经第一神经元的生理完整性。对该神经元的电刺激对于将听觉信号传递至听觉皮层、从而实现声学线索的识别至关重要。
目的： 确定术中eCAP的存在是否影响语前或语后聋成人个体的人工耳蜗植入结局。
方法： 本回顾性横断面研究纳入了因各种病因导致听力损失并接受人工耳蜗植入的成人，包括语前聋或语后聋。从病历中提取术中eCAP结果以及持续使用人工耳蜗12个月后言语识别测试结果的数据。
结果： 分析了121耳的 data，包括101名语后聋个体和20名语前聋个体。在总体样本中，90.9%在术中表现出eCAP存在。在语前聋组中，100%的病例存在eCAP，而语后聋组中89%表现出eCAP存在。与无eCAP者相比，术中eCAP存在的个体在开放式和封闭式测试中均表现出显著更好的言语识别表现。
结论： 在语后聋成人中，89%表现出术中eCAP，这与显著更好的言语识别结局相关。相比之下，语前聋组表现出术中神经反应，但未观察到与言语识别表现存在显著相关性。
英文摘要
INTRODUCTION: The electrically-evoked compound action potential (eCAP) is commonly used to assess the physiological integrity of the auditory nerve's first neuron in cochlear implant (CI) users. Electrical stimulation of this neuron is essential for transmitting auditory signals to the auditory cortex, enabling the recognition of acoustic cues.
OBJECTIVE: To determine whether the presence of intraoperative eCAP influences CI outcomes in adult individuals with pre- or postlingual deafness.
METHODS: The present retrospective cross-sectional study included adults with hearing loss of various etiologies who received a CI, either with pre- or postlingual deafness. Data on intraoperative eCAP results and speech recognition test outcomes after 12 months of consistent CI use were extracted from medical records.
RESULTS: Data from 121 ears were analyzed, comprising 101 individuals with post- and 20 with prelingual deafness. In the overall sample, 90.9% exhibited eCAP presence intraoperatively. In the prelingual group, eCAP was present in 100% of cases, while 89% of the postlingual group showed eCAP presence. Individuals with intraoperative eCAP demonstrated significantly better speech recognition performance compared with those without eCAP, in both open- and closed-set tests.
CONCLUSION: In adults with postlingual deafness, 89% exhibited intraoperative eCAP, which correlated with significantly better speech recognition outcomes. In contrast, the prelingual group demonstrated intraoperative neural responses, but no significant correlation with speech recognition performance was observed.