儿童周围性面神经麻痹——耳部病理的作用
Paediatric Peripheral Facial Nerve Palsy-The Role of Ear Pathology.
文献信息
| PMID | 42728219 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Tal Cozacov |
| 作者单位 | Pediatrics Department B, Schneider Children's Medical Center of Israel, Petach Tikva, Israel. |
| 期刊 | Journal of paediatrics and child health |
| SCI 分区 | Q3 |
| IF | 1.6 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 耳科 |
中文摘要
背景： 近半数获得性周围性面神经麻痹（PFNP）病例病因不明，这种情况被称为贝尔麻痹（BP）。儿童PFNP常可与急性中耳炎（OM）相关。OM相关PFNP（OM-PFNP）与儿童BP在临床病程和预后方面的差异尚未得到充分描述。
方法： 对一家三级儿童医院因非创伤性和非手术相关PFNP住院的儿童进行回顾性审查。
结果： 在177名因面神经麻痹住院的儿童中，46名被排除。本研究共纳入131例PFNP病例，其中80例为OM-PFNP，51例为BP。OM-PFNP患儿就诊时年龄更小（38.8±50.4 vs. 96.6±74.7个月，p<0.001），更常在冬季月份就诊（32.5% vs. 25.5%，p<0.05），并且CRP值更高[中位数（IQR）：1.3（0.18-4.2）vs. 0（0-0）mg/dL，p<0.005]。全身性糖皮质激素使用率无显著差异（87.5% vs. 84.9%，p=0.87）。4名OM-PFNP患儿（BP组无）存在额外的潜在病理。
结论： OM-PFNP患儿就诊时年龄更小，应评估是否存在显著相关的中耳/岩骨病理。
英文摘要
BACKGROUND: Nearly half of the acquired cases of peripheral facial nerve palsy (PFNP) are of unknown aetiology, a condition termed Bell's palsy (BP). PFNP in children can often be associated with acute otitis media (OM). Differences between the clinical course and prognosis in OM-associated PFNP (OM-PFNP) and BP in children are not well characterised.
METHODS: Retrospective review of hospitalised children in a tertiary care children's hospital due to non-traumatic and non-surgery associated with PFNP.
RESULTS: Out of 177 children hospitalised with facial nerve palsy, 46 were excluded. A total of 131 cases of PFNP were included in the study, 80 with OM-PFNP and 51 with BP. Children with OM-PFNP were younger at presentation (38.8 ± 50.4 vs. 96.6 ± 74.7 months, p < 0.001), presented more frequently during the winter months (32.5% vs. 25.5%, p < 0.05), and had a higher CRP value [median (IQR): 1.3 (0.18-4.2) vs. 0 (0-0) mg/dL, p < 0.005]. There was no significant difference in the rate of use of systemic corticosteroids (87.5% vs. 84.9%, p = 0.87). Four children with OM-PFNP (and none of the BP group) had an additional underlying pathology.
CONCLUSIONS: Children with OM-PFNP are younger at presentation and should be assessed for the presence of a significant associated middle ear/petrous bone pathology.