良性阵发性位置性眩晕的复发：危险因素和结局
Recurrence of benign paroxysmal positional vertigo: risk factors and outcomes.
文献信息
| PMID | 42715455 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Ayhan Kars |
| 作者单位 | Erzincan Binali Yıldırım University, Faculty of Medicine, Department of Otorhinolaryngology - Erzincan, Turkey. |
| 期刊 | Revista da Associacao Medica Brasileira (1992) |
| SCI 分区 | Q2 |
| IF | 1.5 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 耳科 |
中文摘要
目的： 良性阵发性位置性眩晕是最常见的外周前庭疾病。尽管手法复位成功，它仍可能复发。虽然已经研究了多种复发的危险因素，但这些因素仍存在争议。本研究旨在确定良性阵发性位置性眩晕复发的潜在危险因素，并为预防性治疗策略的制定提供依据。
方法： 本研究纳入了2019年12月至2022年5月期间因头晕就诊于我们诊所并被诊断为良性阵发性位置性眩晕的301例患者。将伴有和不伴有良性阵发性位置性眩晕复发的两组患者在年龄、性别、高血压、糖尿病、高脂血症、心血管疾病、哮喘、甲状腺功能减退、镁缺乏、维生素D缺乏、维生素B12缺乏和铁缺乏方面进行比较，以探讨这些因素对复发的影响。
结果： 301例患者中有38例（12.6%）观察到复发。两组之间未确定年龄或性别差异。单因素分析显示，高血压（55.3% vs. 29.3%；p=0.003）、维生素B12缺乏（21.1% vs. 6.5%；p=0.007）、高脂血症（26.3% vs. 5.7%；p<0.001）和哮喘（15.8% vs. 5.7%；p=0.035）在复发患者中更为常见。多因素logistic回归分析仅确定高脂血症为危险因素，使复发风险增加约3.7倍（OR 3.71；95%CI 1.36-10.13；p=0.011）。
结论： 考虑潜在的合并症和全身性因素、有效管理现有的合并症以及个体化治疗策略，对于降低良性阵发性位置性眩晕复发率和改善患者生活质量至关重要。
英文摘要
OBJECTIVE: Benign paroxysmal positional vertigo is the most common peripheral vestibular disorder. It can recur despite successful maneuvers. While various risk factors for recurrence have been investigated, these remain controversial. The aim of this study was to identify potential risk factors for benign paroxysmal positional vertigo recurrence and contribute to the development of preventive treatment strategies.
METHODS: The study involved 301 patients who presented to our clinic with dizziness and were diagnosed with benign paroxysmal positional vertigo between December 2019 and May 2022. Two groups, with and without benign paroxysmal positional vertigo recurrence, were compared in terms of age, gender, hypertension, diabetes mellitus, hyperlipidemia, cardiovascular disease, asthma, hypothyroidism, magnesium deficiency, vitamin D deficiency, vitamin B12 deficiency, and iron deficiency to investigate the effects of these factors on recurrence.
RESULTS: Recurrence was observed in 38 (12.6%) of the 301 patients. No age or gender difference was determined between the groups. Univariate analysis showed that hypertension (55.3 vs. 29.3%; p=0.003), vitamin B12 deficiency (21.1 vs. 6.5%; p=0.007), hyperlipidemia (26.3 vs. 5.7%; p<0.001), and asthma (15.8 vs. 5.7%; p=0.035) were more common in patients with recurrence. Multivariate logistic regression analysis identified only hyperlipidemia as a risk factor, raising the risk of recurrence approximately 3.7-fold (OR 3.71; 95%CI 1.36-10.13; p=0.011).
CONCLUSION: Consideration of underlying comorbidities and systemic factors, effective management of existing comorbidities, and individualized treatment strategies are crucial in order to reduce benign paroxysmal positional vertigo recurrence rates and improve patients' quality of life.