用于评估阻塞性睡眠呼吸暂停生活质量的意大利版魁北克睡眠问卷

文献信息

中文摘要

目的： 开发并验证魁北克睡眠问卷的意大利语版本（I-QSQ），用于评估阻塞性睡眠呼吸暂停（OSA）患者的生活质量（QoL）。
方法： 该问卷经过翻译、文化调适和回译。在中度OSA患者中评估了内部一致性和重测信度。在健康受试者中获得了常模值。通过比较患者与对照组的评分，以及将I-QSQ与Epworth嗜睡量表进行相关性分析，评估了结构效度和标准效度。在接受睡眠手术的患者中检验了反应度。
结果： 106例患者和173名对照受试者在无协助的情况下完成了I-QSQ。各领域的内部一致性为可接受至优秀（Cronbach's α = 0.71-0.9），重测信度高（ICC = 0.88-0.96）。患者在所有领域的评分均显著低于对照组（p < 0.001）。观察到I-QSQ与Epworth嗜睡量表评分之间呈负相关（r = -0.54）。术后患者的I-QSQ总分显著改善。
结论： I-QSQ是一种可靠、有效且具有反应度的工具，可用于评估意大利语睡眠呼吸暂停患者的生活质量，并可在临床实践和研究中有效使用。

英文摘要

OBJECTIVE: To develop and validate the Italian version of the Quebec Sleep Questionnaire (I-QSQ) for assessing quality of life (QoL) in patients with obstructive sleep apnoea (OSA).
METHODS: The questionnaire was translated, culturally adapted, and back-translated. Internal consistency and test-retest reliability were evaluated in patients with moderate OSA. Normative values were obtained in healthy subjects. Construct and criterion validity were assessed by comparing scores of patients and controls, and by correlating I-QSQ with the Epworth Sleepiness Scale. Responsiveness was examined in patients undergoing sleep surgery.
RESULTS: One hundred-six patients and 173 control subjects completed the I-QSQ without assistance. Internal consistency was acceptable to excellent across domains (Cronbach's α = 0.71-0.9), and test-retest reliability was high (ICC = 0.88-0.96). Patients scored significantly lower than controls in all domains (p < 0.001). A negative correlation was observed between I-QSQ and Epworth Sleepiness Scale scores (r = -0.54). Post-surgical patients showed significant improvement in I-QSQ total score.
CONCLUSIONS: I-QSQ is a reliable, valid, and responsive tool for evaluating QoL in Italian-speaking patients with sleep apnoea and can be effectively used in clinical practice and research.