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跨性别女性直接喉软骨成形术后的客观嗓音结果:一项特定技术的队列研究

Objective acoustic voice outcomes following direct laryngochondroplasty in transgender women: a technique-specific cohort study.

临床研究咽喉科IF 2.3Q1

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中文摘要

目的: 评估跨性别女性接受直接经前庭喉软骨成形术(DTVLCP)后特定技术的客观嗓音结果。
方法: 一项在三级转诊中心进行的回顾性队列研究。纳入2019年12月至2025年7月期间接受DTVLCP的所有跨性别女性。使用标准化声学参数分析其术前和术后嗓音录音,包括基频(F0)、共振峰频率(F1、F2)、基频微扰、振幅微扰和最长发声时间(MPT)。亚组分析比较了有和无主观嗓音变化的患者,以及接受单纯手术与联合手术的患者。
结果: 28名跨性别女性(平均年龄27.8岁)的嗓音录音可用于声学分析。所有患者术后声带运动均得以保留。7名患者报告了主观嗓音变化。对该队列嗓音录音的术前和术后声学分析进行比较,未发现所测声学参数(平均F0、F1、F2、基频微扰、振幅微扰和最长发声时间)有统计学显著变化。在报告术后主观嗓音变化的患者亚组(n=7)与未报告者(n=21)之间,以及接受单纯DTVLCP的患者(n=9)与接受该手术联合下面部女性化手术的患者(n=19)之间,均未发现显著的声学变化。
结论: DTVLCP与所测声学嗓音参数的显著客观变化无关。这些发现支持DTVLCP在嗓音方面的安全性,并在现有数据主要来自主观报告和异质性手术方法的领域中提供了特定技术的证据。

英文摘要

PURPOSE: To evaluate objective technique-specific voice outcomes following direct transvestibular laryngochondroplasty (DTVLCP) in transgender women.
METHODS: A retrospective cohort study conducted at a tertiary referral Center. Included were all transgender women who underwent DTVLCP from December 2019 to July 2025. Their pre- and postoperative voice recordings were analyzed using standardized acoustic parameters, including fundamental frequency (F0), formant frequencies (F1, F2), jitter, shimmer and maximum phonation time (MPT). Subgroup analyses compared patients with and without subjective voice changes and those undergoing isolated versus combined procedures.
RESULTS: Voice recordings of 28 transgender women (mean age 27.8 years) were available for acoustic analysis. Postoperative vocal fold movement was preserved in all patients. Seven patients reported subjective voice change. A comparison of pre- and postoperative acoustic analysis of the cohort's voice recordings revealed no statistically significant changes in the measured acoustic parameters (mean F0, F1, F2, jitter, shimmer, and maximum phonation time). No significant acoustic changes were found between the subgroup of patients who reported subjective postoperative voice changes (n = 7) and that of patients who did not (n = 21), and between patients who underwent isolated DTVLCP (n = 9) and those who had the procedure combined with lower facial feminization surgery (n = 19).
CONCLUSION: DTVLCP was not associated with significant objective changes in the measured acoustic voice parameters. These findings support the safety of DTVLCP with respect to voice and provide technique-specific evidence in a field where existing data are largely derived from subjective reports and heterogeneous surgical approaches.